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Symbol
Name
ID 		Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
MGI:88588
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations
Human Phenotypes
Increased circulating IgA level
Increased circulating IgG level
Decreased circulating antibody level
Paraproteinemia
Abnormality of blood and blood-forming tissues
Abnormal erythrocyte enzyme concentration or activity
Anemia
Hemolytic anemia
Leukocytosis
Leukopenia
Abnormal granulocyte morphology
Abnormal basophil morphology
Acute lymphoblastic leukemia
Ph-positive acute lymphoblastic leukemia
T-cell acute lymphoblastic leukemias
Acute myeloid leukemia
Chronic myelogenous leukemia
Myeloproliferative disorder
Superficial thrombophlebitis
Thrombocytopenia
Thrombocytosis
Hematological neoplasm
Lymphoma
Multiple myeloma
Splenomegaly
Hepatosplenomegaly
Disease(s) Associated with CYP1A1
acute lymphoblastic leukemia
acute myeloid leukemia
Behcet's disease
chronic myeloid leukemia
cystic fibrosis
multiple myeloma
porphyria cutanea tarda
systemic lupus erythematosus

Mouse Phenotypes
decreased thymus weight
small thymus
decreased hematocrit
abnormal hemoglobin content
increased hemoglobin content
increased neutrophil cell number
decreased lymphocyte cell number
decreased leukocyte cell number
decreased spleen weight
small spleen
Availability Mouse Genotype
Cyp1a1tm1.1Dwn/Cyp1a1tm1.1Dwn
Cyp1a1tm4.1Dwn/Cyp1a1tm4.1Dwn
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory